Host-Pathogen

c elegansThe ability of a bacterium to establish an infection within a host is dependent on both host and pathogen factors.  Classically, the model organism for study host-pathogen interactions with Salmonella has been the mouse.  Recently, the nematode Caenorhabditis elegans has been used as an alternative to the mouse model for a variety of bacteria.  Previous literature has shown thatS almonella enterica server Typhimurium is able to establish infection in C. elegans. Current projects aim to characterize the C. elegans model for other serovars, as well as identify virulence factors of Salmonella important for virulence and host factors that prevent infection.

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s

%d bloggers like this: